Postdoc in Single-Molecule and Single-Vesicle Imaging of Neurodegenerative Diseases Full-time NEW

Postdoc In Single-Molecule And Single-Vesicle Imaging Of Neurodegenerative Diseases

The Department of Chemistry at Aarhus University invites you to apply for a postdoctoral position within the ERC Starting Grant-funded project SPARTA. Are you interested in understanding the molecular mechanisms underlying neurodegenerative diseases using cutting-edge fluorescence microscopy and single-vesicle imaging? Do you want to contribute to uncovering how protein aggregation and membrane interactions drive the development of Parkinson's disease?

We are seeking a highly motivated and ambitious postdoctoral researcher to join our research group at the Department of Chemistry, Aarhus University. The successful candidate will develop and apply advanced single-molecule and single-vesicle imaging approaches to investigate the dynamic interactions between α-synuclein oligomers and biological membranes, aiming to uncover fundamental mechanisms of neurodegeneration and contribute to the development of novel strategies for early disease detection.

This is a fixed-term 2-year position starting on 1 February 2027, or as soon as possible thereafter.

The successful candidate will join the ERC Starting Grant-funded project SPARTA, aiming to uncover the molecular mechanisms of α-synuclein aggregation and membrane interactions in Parkinson's disease. The position will primarily involve:

• Investigating α-synuclein aggregation and interactions with lipid membranes.
• Developing and applying advanced single-molecule and single-vesicle fluorescence microscopy.
• Exploring how membrane composition and properties influence protein aggregation and membrane disruption.
• Performing quantitative image analysis and computational data analysis.
• Developing novel single-vesicle assays for studying neurodegenerative disease mechanisms.

The research will be conducted in an interdisciplinary environment at the Department of Chemistry, Aarhus University, in collaboration with researchers in biophysics, molecular biology, and neuroscience.

We value scientific curiosity, creativity, independence, and a collaborative mindset.