Postdoc Oral Lipid Based Formulations Full-time

Postdoctoral Scholar (Postdoc)

We are seeking a talented Postdoctoral Scholar (Postdoc) to work in a highly collaborative environment for a two-year assignment during which you will explore advanced in vitro characterization methods that connect lipid formulation behavior to drug delivery potential ultimately aiming to design next-generation lipid based formulation strategies for beyond rule of five (bRo5) drug candidates.

Key responsibilities

In this role, you will:

• Build and explore an advanced in vitro characterization toolbox e.g. coupling dissolution, lipolysis, precipitation/crystallization, mucus penetration, and permeation readouts for lipid-based formulations.
• Explore downscaling/high-throughput feasibility for e.g. lipolysis and dissolution-permeation workflows to enable efficient screening and optimization.
• Design and optimize next-level lipid formulation strategies for the oral delivery of bRo5 molecules
• Support in vivo translation e.g. contributing to rat PK/lymphatic transport studies and mechanistic experiments
• Communicate scientific outcomes through internal presentations and scientific forums and contribute to manuscript preparation and publication strategy consistent with IP guidance.

Required qualifications

• PhD (or near completion) in Pharmaceutical Sciences, Chemical Engineering, Chemistry, Bioengineering, or a closely related discipline.
• Demonstrated ability to design and execute experimental research with scientific independence (literature review, planning, lab execution, data analysis, reporting).
• Experience relevant to the project focus: lipid-based formulations and/or biopharmaceutics tools that link formulation behavior (dispersion/dissolution/digestion/precipitation) to delivery potential (permeation).
• Strong written and verbal communication skills in English and a track record of scientific output (publications/presentations and/or patents).
• Willingness to work on-site in Beerse, Belgium with hands-on lab activities.

Preferred qualifications

• Experience with one or more of: lipolysis/digestion models, dissolution-permeation methods, membrane permeability models (e.g., PAMPA variants), mucus assays, precipitation/crystallization analytics, or phase characterization during digestion/dissolution.
• Familiarity with lipid-based formulation optimization strategies and/or exploration of in-silico tools to guide formulation design (e.g., COSMO).
• Exposure to translational modeling and/or in vivo study support (PBPK/PK; oral absorption/lymphatic transport).

The anticipated base pay range for this position is:

€60,000.00 – €96,255.00

Benefits:

In addition to base pay, we offer the following benefits*: an annual bonus with set target (% of pay) depending on pay grade / location, where the actual amount is based on the employees' and companies' performance of the previous calendar year, or sales commissions. Moreover, we offer vacation days, parental leave for a minimum of 12 weeks, bereavement leave, caregiver leave, volunteer leave, well-being reimbursement, programs for financial, physical and mental health. We also offer service anniversary and recognition awards, and subject to the terms of their respective plans, employees – and in some location's eligible dependents – can participate in several insurance plans. For more information, visit Employee benefits | Supporting well-being & career growth | Johnson & Johnson Careers.

*This is for informative purposes only. Amounts and actual benefits may vary by location and are subject to change.