Postdoctoral Research Associate – Oncology Full-time

Postdoctoral Research Position

Location: SAINT LOUIS, MO 63110

Position Summary: Postdoctoral Research (Scholar or Associate) Position Open in the Jaebok Choi Lab in Department of Medicine, Division of Oncology. Area of expertise: Transplant Immunology focused on T cells.

The Choi Lab is seeking a postdoctoral researcher to work on T cell biology in mouse models of diseases, including, but not limited to, graft-vs-host disease (GvHD), inflammatory bowel disease (IBD), and/or experimental autoimmune encephalomyelitis (EAE). Using unbiased genome-wide CRISPR/Cas9 guide RNA library screens and whole kinome analyses, we have identified promising novel therapeutic targets such as VLDLR, GAS6/TAM, and PKN1 whose targeting may separate the inflammatory diseases from the beneficial healthy immune responses, such as graft-vs-leukemia/tumor effects, anti-tumor and anti-infection responses. For translational approaches, the postdoctoral researcher may occasionally analyze human patient samples. In addition to high-quality research facilities, career and professional development training for postdoctoral researchers is provided through the Career Center, Teaching Center, Office of Postdoctoral Affairs, and campus groups.

Job Description: Primary Duties & Responsibilities:

Information on being a postdoc at WashU in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/.

Please see departmental websites for the more information at https://profiles.wustl.edu/en/persons/jaebok-choi/ and https://oncology.wustl.edu/people/jaebok-choi-phd/.

Trains under the supervision of a faculty mentor including (but not limited to):

• Manages their own project, which should lead to a first author publication.
• Develops expertise in T cell biology, mouse models of GvHD/GvL, IBD, or EAE, CRISPR/Cas9 guide RNA library screening, bioluminescence imaging, intestinal organoids, and multicolor flow cytometry.
• Develops proficiency in career skills, including writing, public speaking, networking, and critical evaluation of scientific literature.
• Presents scientific work both inside and outside the University with excellent oral communication skills.
• Assists with grant preparation and reporting.
• Prepares and submits papers on research.
• Assists in the design of research experiments.
• Evaluates research findings and assists in the reporting of the results.
• Conscientious discharge of their research responsibilities.
• Maintains conformity with ethical standards in research.
• Maintains compliance with good laboratory practice including the maintenance of adequate research records.
• Engages in open and timely discussion with their mentor regarding possession or distribution of material, reagents, or records belonging to their laboratory and any proposed disclosure of findings or techniques privately or in publications.
• Collegial conduct towards co-trainees, staff members and members of the research group.
• Adherence to all applicable University policies, procedures and regulations. All data, research records and materials and other intellectual property generated in University laboratories remain the property of the University.

Working Conditions: This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.

Salary Range: Base pay is commensurate with experience.

Applicant Special Instructions: Interested candidates should submit their curriculum vitae, statement of research interests and contact information of three references via e-mail to Dr. Jaebok Choi at jchoi25@wustl.edu.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications: Education: Ph.D., M.D. Or Equivalent Terminal Or Doctoral Degree.

More About This Job: At WashU, postdoctoral appointments: Have a 5-year term limit that includes previous experience.