We are seeking a highly motivated Postdoctoral Research Fellow to develop next-generation AI methods for modeling disease microenvironments using spatial omics, digital pathology, and language-model–based cell representations. This is a joint role spanning Oncology R&D and Inflammation & Immunology R&D, designed to accelerate cross-portfolio discovery through integrative computational modeling of tissue architecture, immune engagement, and disease biology.
The successful candidate will work on an interdisciplinary project aimed at understanding how cellular states, spatial interfaces, and tissue architecture jointly shape therapeutic response in human disease. The postdoc will help build an agentic AI platform that integrates cell-state language models, boundary-resolved spatial profiling, and digital pathology foundation models to generate interpretable, mechanistically grounded insights from multimodal tissue data.
This role offers the opportunity to contribute to both oncology and immunology/inflammation research programs, with a strong emphasis on translational impact, biomarker discovery, reverse translation, and human disease stratification.
Role Responsibilities The project is centered on three major scientific ideas:
To address these questions, the postdoc will help develop and apply methods that combine:
Reporting Structure
This postdoctoral position will be jointly monitored and mentored by investigators from both Oncology R&D and Inflammation & Immunology R&D. The postdoc will operate in a highly collaborative matrix environment and will be expected to engage with scientific mentors and stakeholders across both therapeutic areas.
Required Qualifications
Preferred Qualifications
Additional Information
The annual base salary for this position ranges from $64,600.00 to $107,600.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com . This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Tagged as: Life Sciences
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