Postdoctoral studies in the Mechanistic Proteomics of the Gut-Brain Axis (scholarship) Full-time

Postdoctoral Studies in the Mechanistic Proteomics of the Gut-Brain Axis (Scholarship)

The Department of Microbiology, Tumor and Cell Biology (MTC) at Karolinska Institutet conducts research and teaching within immunology, infection biology, cell biology and cancer. Our key words are multidisciplinary, bridging, national and international collaborations.

We are looking for a Postdoc to join Dr. Amir Ata Saei's group. This multidisciplinary team has a solid background in using proteomics and bioinformatics to study disease. The specific postdoctoral project involves the application of proteomics and biochemistry tools to dissect the molecular targets and mechanisms of selected microbiome-derived metabolites within the gut brain axis. If you are interested in making original mechanistic discoveries, this position is for you.

The division is a leading hub for cutting-edge research on cancer and metabolic disease. The division's research is driven by a team of distinguished scientists, each contributing unique expertise and innovative approaches to the field.

The project will leverage state-of-the-art proteomics, chemical biology, and biochemical approaches to identify direct protein targets of microbiome-derived metabolites and define their mechanisms in neurodegeneration. The applicant will perform proteomics experiments to identify candidate target proteins and conduct follow-up experiments in relevant in vitro and in vivo models to validate findings. The applicant is expected to set up novel experimental approaches within the research group and to actively participate in other lab projects, collaborate, contribute to manuscript and grant writing, and present results to general and specialized audiences.

We are looking for an applicant with the profile below (requirements):

• The successful applicant should have a strong publication record.
• Strong English skills, both written and spoken.
• The applicant should be enthusiastic and motivated with a strong background in neurobiology, molecular biology, chemical biology, microbiome research, or related biomedical disciplines.
• The applicant should have experience with neuronal models.
• The candidate should be able to work both independently and collaboratively.

Meritorious for the position:

• Specific experience in microscopy techniques is meritorious.
• Experience in basic data analysis and bioinformatics is meritorious.
• Experience in proteomics is meritorious.
• Experience with animal experiments is highly meritorious.

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.