Principal Research Scientist II, Process Chemistry Full-time NEW

Principal Research Scientist II

AbbVie Process Chemistry is responsible for the chemical development of AbbVie's clinical candidates. We are looking for a highly motivated Principal Research Scientist II who can make scientific contributions and develop strategies, timelines and key activities across drug substance modalities, including small molecules. The candidate must be able to mentor and develop staff with experimental approaches to solve difficult scientific and technical challenges. The candidate will be an integral part of project teams and will be responsible for developing the synthetic process and executing activities required for drug substance process development. Working with cross-functional colleagues, the candidate will develop productive collaborations and communications with scientific teams.

Responsibilities:

• The candidate will participate and/or lead project teams associated with drug substance process development and characterization.
• Develop and characterize drug substance processes in the laboratory and translate them to scalable processes.
• Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management. Mentor staff in troubleshooting strategic and experimental issues.
• Author and review key regulatory documents, laboratory data, technical memos and reports.

The position involves multi-disciplinary interactions with organic chemists, analytical chemists, engineers, drug product development, and program management.

The candidate will identify and nurture ideas for continuous improvement activities and initiatives within the department.

The candidate will be responsible for setting project strategies, defining project responsibilities and timelines, developing control strategies, providing leadership in a matrixed team setting and developing robust processes for cGMP manufacturing.

Qualifications:

• BS (16+ years); MS (14+ years) or PhD (8+ years) in Chemistry or allied field, with 8+ years of previous work experience in a pharmaceutical laboratory setting.
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.
• Experience with GMP drug substance manufacturing and process development.
• Experience in managing and developing scientific leaders.
• The successful candidate will have a strong understanding of modern organic chemistry, mechanistic theory, process development, control strategy development, and regulatory starting material strategies.

Key AbbVie Competencies:

Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.

• Learns fast, grasps the “essence” and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

Additional Information:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only – to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

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Pay Range:

$ 141500 – 268500 USD

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USD

Where We Work

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.