Principal Scientist (Director) – Rheumatology Outcomes Research Full-time NEW

Principal Scientist/Director

Under the guidance of an Executive Director, the Principal Scientist/Director has primary responsibility for developing value evidence strategies, and planning/managing real world and economic evidence activities for pipeline assets in rheumatology to meet the value evidence needs of clinicians, payers, policymakers, HTA/reimbursement agencies and health systems globally. The ability to participate and lead cross-functional teams is a critical part of this role.

Types of studies executed include prospective and retrospective observational studies to characterize disease burden and epidemiology, treatment patterns, healthcare resource utilization and costs, physician and patient satisfaction surveys, clinical and patient reported outcomes assessments, systematic reviews and meta-analyses, and economic modelling. Key responsibilities also include development of American Managed Care Pharmacy (AMCP) dossiers for US payers, and Global Value Dossiers for use by local subsidiaries in their HTA submissions. Incumbent is also expected to contribute to product development and marketing strategies throughout the lifecycle to ensure that product value is defined and developed to achieve optimal market/patient access and reimbursement. The incumbent is expected to work cross-functionally with clinical development, medical affairs, biostatistics, market access, commercial and country affiliates and may have direct interactions with health technology assessment (HTA) agencies, reimbursement decision makers and national immunization technical advisory groups.

Responsibilities and Primary Activities

• Leads value evidence teams and develops value evidence strategies for in-line and pipeline products. Obtains senior management approval of evidence generation plans. Provides outcomes research leadership on cross-functional regional and global teams
• Critically assesses drivers and barriers to reimbursement and market access, and provides input into clinical, regulatory, payer/access, marketing and evidence generation strategies and programs
• In collaboration with internal teams and external partners, designs studies, authors study protocols, develops measurement questionnaires, case report forms, data analysis plans, final study reports, scientific presentations, and publications
• Responsible for study-related contracting, budgets, and vendor/partner management and to ensure study conduct is aligned with company Policies and SOPs and world-wide regulations and standards, including Good Pharmacoepidemiology Practice (GPP) for applicable work.
• Develops American Managed Care Pharmacy (AMCP) dossiers for US payers, and Global Value Dossiers for use by local subsidiaries in their local HTA submissions
• Develops supplementary clinical data package in close partnership with markets and HTA statistics group for submission to HTA agencies
• Supports country affiliates to understand local evidence generation needs, adapts health economic evaluations, customizes outcomes research documents, such as protocols and reimbursement dossiers, according to local requirements
• Works closely with cross-functional teams to effectively communicate outcomes research and health economic modelling data internally and to external stakeholders
• Maintains awareness of new scientific and methodological developments within therapeutic area
• Builds relationships with scientific experts worldwide
• Presents outcomes research data at national and international congresses and publishes articles in scientific journals

Required Qualifications, Skills, & Experience

Minimum

• Doctoral degree (PhD, DrPH, ScD, PharmD) in relevant discipline (health services research, outcomes research, epidemiology, public health, health economics, pharmacoeconomics, pharmacy administration)
• 7+ years experience post degree

Required Skills:

Health Economics, Health Technology Assessment (HTA), Medical Affairs, Outcomes Research, Product Marketing, Public Health, Public Health Research, Rheumatology, Stakeholder Relationship Management, Strategic Planning

The salary range for this role is $190,800.00 – $300,300.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.