Principal Scientist I, Neurobiology of Obesity Full-time NEW

Principal Scientist, Obesity Therapeutics

AbbVie is expanding its presence in Obesity Therapeutics and is seeking a Principal Scientist to participate in external innovation and diligence efforts to advance the early obesity pipeline. This individual will report to a scientific director of obesity and primarily focus on external innovation activities for obesity assets.

Responsibilities:

• Support external collaborations and licensing opportunities to diversify the pipeline by serving as the Obesity Discovery lead in Search & Evaluation diligence teams. Use personal scientific expertise to advise on scientific merit and drive external innovation.
• Perform literature/intelligence searches to determine scientific and technical approaches for discovery of novel obesity targets emphasizing CNS regulation of energy balance with potential utility in additional indications (neurological disorders, autoimmune disorders).
• Serve as the Obesity Discovery lead in cross functional teams to expand obesity targets into other key therapy areas at AbbVie including but not limited to neuroscience and immunology.
• Coordinate in vitro/in vivo PoC studies for preclinical assets, working with contract research organizations and academic labs to complete key preclinical experiments.
• Apply experience to analyze preclinical PK, in vitro, in vivo data sets for obesity related assets, and to ensure scientific integrity throughout the process.
• Prepare scientific reports and presentations related to pre-clinical obesity assets.
• Design MoA experiments, review protocols, and data sets for late-stage clinical assets.
• Responsible for completing these tasks with minimal supervision.

Qualifications:

• PhD scientist with post-doctoral training in neuroscience, biology or related biological discipline
• 6+ years of independent research experience in industrial or academic setting
• Content expertise in obesity related scientific areas including CNS regulation of energy balance, brain peripheral cross-talk and pharmacological manipulation of energy balance
• Proven record of scientific achievements as assessed by peer reviewed publications
• Proficient with AI tools, graphing and data analysis tools
• Capable of performing platform talks at international conferences
• Excellent organizational, oral and written communication skills
• Complex problem solving and excellent attention to detail
• Ability to manage time independently and effectively to achieve goals
• Experience in project management and cross functional/disciplines working is a plus

Key Stakeholders: Obesity Discovery Research Scientific Directors, Search & Evaluation Obesity Teams

Compensation Range: $124500 – 236500 USD