Principal/Sr. Principal Scientist, CMSC Global Process Hazard Evaluation Full-time

Principal/Sr. Principal Scientist in CMSC (Clinical Manufacturing & Supply Chain) Global Process Hazard Evaluation

The Principal/Sr. Principal Scientist in CMSC (Clinical Manufacturing & Supply Chain) Global Process Hazard Evaluation is an experienced professional responsible for designing and conducting comprehensive chemical process hazard assessments, evaluating results, and delivering recommendations to establish a basis of safety for process scale-up. The individual will provide technical expertise on process safety matters to R&D and commercial teams, actively contribute to the safe development, scale-up, and design of chemical processes, and participate in project meetings, laboratory risk assessments, and campaign evaluations. Additionally, the role supports the development and implementation of innovative technologies within the function while promoting Process Safety Awareness across the organization.

Key Responsibilities

• Timely completion and communication of Chemical Process Hazards Evaluations for allocated projects prior to scale-up in Pilot Plant or transfer to commercial manufacturing.
• Zero incidents during Pilot Plant scale-up or commercial manufacturing directly contributed to insufficient evaluation and communication of completed chemical reaction hazard assessments.
• Assess chemical reaction hazards and report findings and recommendations to agreed global standards.
• Continuously review and improve current hazard evaluation practices and equipment to maintain high standards of service.
• Contribute to risk assessments prior to scale-up lab and pilot plant runs to communicate hazards to operational personnel.
• Support the Technical Transfer of projects into manufacturing through design of safe operating space, risk, maloperation, and waste assessments.
• Deliver Process Safety training materials to raise awareness within the organization and increase the competency of colleagues.
• Maintain an efficient communication process with customers, ensuring that process safety issues are understood and acted on appropriately by the project teams and customer groups.

Basic Qualification

• Bachelor's degree in chemistry or chemical engineering (or equivalent).
• 5+ years of industrial experience in process safety or scale-up environments.

Preferred Qualification

• Demonstrated mastery in the principles of chemical reaction hazard assessment and application of process safety technologies, including:
• Ability to independently design, execute, modify an experimental plan for process hazard assessment and evaluate, quantify, and interpret the results.
• Ability to independently translate the results of hazard evaluation into recommendations for safe scale-up.
• Demonstrated record of recognizing a process without a basis of safety and working with project colleagues to modify the process to establish of a BoS.
• Demonstrated record of working with pilot plant colleagues to identify concerns and recommend solutions.
• Demonstrated knowledge and application of chemical and/or engineering aspects of Process Safety.
• Full execution of chemical process hazard assessment, and participation/leadership of risk assessment activities.
• Subject Matter Expert (SME) for Process Safety knowledge and expertise to less experienced personnel.
• Consistent demonstration of communication, influencing, customer focus, working across boundaries and sense of urgency behaviors.

Work Arrangements:

• This role offers an on-site (5 days) working model; Remote or fully home-working arrangements are not available for this role.

Skills

• Analytical Chemistry, Batch Record Review, Chemical Processes, Enzymatic Reactions, Experimental Methods, External Manufacturing, Organometallic Chemistry, Problem Analysis, Process Scale Up, Purification Methods, Synthetic Chemistry, Technical Writing, Technology Transfer

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a purpose to unite science, technology and talent to get ahead of disease together. We aim to positively impact the health of 2.5 billion people by the end of the decade, as a successful, growing company where people can thrive. We get ahead of disease by preventing and treating it with innovation in specialty medicines and vaccines. We focus on four therapeutic areas: respiratory, immunology and inflammation; oncology; HIV; and infectious diseases – to impact health at scale.

People and patients around the world count on the medicines and vaccines we make, so we're committed to creating an environment where our people can thrive and focus on what matters most. Our culture of being ambitious for patients, accountable for impact and doing the right thing is the foundation for how, together, we deliver for patients, shareholders and our people.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the appropriate Recruitment Staff by emailing us at – usrecruitment.adjustments@gsk.com

GSK is an Equal Opportunity Employer. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), parental status, national origin, age, disability, genetic information (including family medical history), military service or any basis prohibited under federal, state or local law.