R00148615 – Principal Scientist I, Energy Homeostasis Full-time

Principal Scientist, Obesity Therapeutics

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

Purpose: AbbVie is expanding its presence in Obesity Therapeutics and is seeking a Principal Scientist to participate in external innovation and diligence efforts to advance the early obesity pipeline. This individual will report to a scientific director of obesity and primarily focus on external innovation activities for obesity assets.

Responsibilities:

• Support external collaborations and licensing opportunities to diversify the pipeline by serving as the Obesity Discovery lead in Search & Evaluation diligence teams. Use personal scientific expertise to advise on scientific merit and drive external innovation.
• Perform literature/intelligence searches to determine scientific and technical approaches for discovery of novel obesity targets emphasizing energy metabolism and energy expenditure leading to weight loss with potential utility in additional indications (neurological disorders, autoimmune disorders).
• Serve as the Obesity Discovery lead in cross functional teams to expand obesity targets into other key therapy areas at AbbVie including but not limited to neuroscience and immunology.
• Coordinate in vitro/in vivo PoC studies for preclinical assets, working with contract research organizations and academic labs to complete key preclinical experiments.
• Apply experience to analyze preclinical PK, in vitro, in vivo data sets for obesity related assets, and to ensure scientific integrity throughout the process.
• Prepare scientific reports and presentations related to pre-clinical obesity assets.
• Design MoA experiments, review protocols, and data sets for late-stage clinical assets.
• Responsible for completing these tasks with minimal supervision.

Qualifications:

• Ph.D scientist with post-doctoral training in neuroscience, biology or related biological discipline
• 6+ years of independent research experience in industrial or academic setting
• Content expertise in obesity related scientific areas including CNS regulation of energy balance and peripheral energy metabolism, brain peripheral cross-talk and pharmacological manipulation of energy balance
• Proven record of scientific achievements as assessed by peer reviewed publications
• Proficient with AI tools, graphing and data analysis tools
• Capable of performing platform talks at international conferences
• Excellent organizational, oral and written communication skills
• Complex problem solving and excellent attention to detail
• Ability to manage time independently and effectively to achieve goals
• Experience in project management and cross functional/disciplines working is a plus

Key Stakeholders:

• Obesity Discovery Research Scientific Directors, Search & Evaluation Obesity Teams

Additional Information:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

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Pay Range: $124500 – 236500 USD

Where We Work:

Role is primarily site- or office-based but can occasionally be performed remotely. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.