Scientist I/II Full-time

AbbVie Scientist I

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

The Quantitative, Translational & ADME Sciences (QTAS) Department at AbbVie, Inc. in North Chicago, IL is seeking a Scientist I to join the Non-Regulated Bioanalysis group. This role supports high-throughput processing of samples from biological matrices and LC-MS/MS-based bioanalysis. The ideal candidate will have experience in bioanalytical sample preparation using a range of extraction techniques, operational workflows, data analysis, review, and reporting.

This position is well suited for a detail-oriented, motivated scientist who thrives in a fast-paced, collaborative environment and is committed to delivering high-quality results across multiple projects under tight deadlines. The role also involves partnering with cross-functional teams to align bioanalytical processes with scientific and business needs.

Key Responsibilities

• Support LC-MS/MS-based PK/PD, efficacy, and exploratory toxicology bioanalytical studies
• Conduct and optimize sample extraction using protein precipitation, liquid/liquid extraction, or solid-phase extraction methods
• Operate and troubleshoot robotic systems (Hamilton, Tecan) and LC-MS/MS platforms (Leap/CTC PAL autosamplers, Agilent HPLCs, Sciex 5500/6500 triple quadrupole mass spectrometers) and software such as Discovery Quant, Analyst, Sciex OS, and MassHunter
• Troubleshoot pre-analytical and bioanalytical issues
• Maintain accurate documentation of work, including LIMS records, electronic notebooks, test methods, and protocols
• Collaborate with teams across Discovery and QTAS to support bioanalysis
• Train and mentor junior scientists as needed

Qualifications

• Bachelor's degree with 5 years of experience, or Master's degree with 2 years of experience, in Chemistry, Analytical Chemistry, or a related field
• Hands-on experience in bioanalysis of small molecules, peptides, and large molecules in the pharmaceutical industry, including sample preparation and method development
• Strong interpersonal skills with the ability to work independently and collaboratively in a high-throughput setting
• Experience operating automated liquid handling robotic platforms such as Hamilton or equivalent systems
• Experience operating CTC-PAL and Agilent liquid chromatography instruments, as well as LC-MS/MS platforms such as AB Sciex triple quadrupole mass spectrometers or equivalent systems
• Experience with electronic laboratory notebook software and Laboratory Information Management Systems (LIMS)
• Strong instrument and assay troubleshooting skills
• Experience with process development or optimization preferred

Compensation Range: $78500 – 141000 USD

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.