Scientist I, Molecular Biology Full-time

Antibody Development Scientist

Work Schedule: Standard (Mon-Fri)

Environmental Conditions: Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description:

Thermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $44 billion. Our mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our innovative laboratory technologies & services make it easier for customers.

About Team: Antibody Team

The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of the team include design, development, purification, conjugation, and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is product development and creation of product specific information to promote research use.

Role & Responsibilities

To be a member of the molecular biology core facility within an antibody development team through the advancement of innovative molecular biology techniques to enable high throughput recombinant antibody platforms.

• Work in a fast paced environment towards antibody development & testing
• Execute molecular biology techniques such as PCR, primer and vector design, DNA and RNA extraction and analysis, high throughput cloning
• Meticulous experimental planning and execution to meet program goals.
• Timely record keeping of results into data sheets and laboratory note-books.
• Regular mining of literature and keeping oneself up to date with developments in the field of antibody development.
• Compilation and presentation of data in written and oral formats. Active participation in team meetings.
• Attention to detail and adherence to schedules.

Candidate Requirement:

Applicants should have a Master's degree or equivalent with 0-4 years' experience or a PhD in a life sciences field (submitted within the last one year) with a strong focus on molecular biology, immunology, biotechnology, or biochemistry.

• Extensive hands on experience with molecular biology techniques such as PCR, primer and vector design, DNA and RNA extraction and analysis, high throughput cloning methods
• Experience with Next Generation Sequencing platforms including library preparation, and handling of sequencers
• Experience with bioinformatic analysis of sequencing data, particularly antibody sequencing
• Knowledge of programming languages such as Python or R is a plus
• Experience or familiarity with immunoassays such as ELISAs, Western Blotting, Immunocytochemistry, and/or immunohistochemistry.
• Experience with antibody development and engineering including hybridoma, display technologies, single B cell, and other antibody platforms is desirable.
• Experience in high throughput methods including automation is desirable
• Experience in establishing new protocols and workflows is desirable
• Excellent troubleshooting and problem-solving skills to identify and troubleshoot technical challenges and provide suitable solutions
• Flexibility and adaptability to work in a fast-paced research environment.
• Proficiency in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism.

The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate.

Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates.

We offer attractive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. We offer employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer a company culture that stands for integrity, intensity, involvement, and innovation.