Scientist I, Protein Biology Full-time

Job Title

Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer.

About the Team

The Antibody Team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is recombinant antibody development and creation of product specific information to promote research use.

Key Responsibilities

• Design and execute protein and molecular biology assays to support antibody development and validation programs.
• Meticulous experimental planning and execution to meet program goals.
• Timely record keeping of results into data sheets and laboratory note-books.
• Attention to detail and adherence to schedules.
• Communicate results clearly—in team meetings, written reports, and data presentations.
• Regular mining of literature and keeping oneself up to date with developments in field of antibody development.
• Troubleshoot technical challenges and propose practical solutions to keep projects moving.

Qualifications & Experience

Education

• Applicants should hold a degree in a relevant life sciences discipline (protein biology, molecular biology, biochemistry, immunology, biotechnology, or a related field) at one of the following levels:
• PhD (graduated within the last one year)
• Master's degree with 1-3 years of relevant research experience

Technical Skills & Experience

• Experience in molecular biology, which could include nucleic acid extraction, PCR, and cloning.
• Experience with bioinformatics such as BLAST, pairwise and multiple sequence analysis, design and construction of expression vectors, codon optimization, PCR primer design.
• Experience with molecular biology software such as Snapgene, CLC Workbench or Geneious. Basic knowledge of computational biology, biological databases, or scripting is a plus.
• Prior experience in single cell molecular biology workflows, next generation sequencing and/or display technologies is desirable.
• Knowledge and experience in protein purification, immunoassays such as ELISA, Western Blotting, Immunocytochemistry, Immunohistochemistry or Flow cytometry, and cell culture techniques. Prior experience with protein or antibody conjugation will be a plus.
• Theoretical or practical experience in antibody development platforms is advantageous.
• Project or work experience such as publications, project reports or thesis work.
• Proficiency in MS Office applications such as Word, Power Point, Excel and strong statistical knowledge or familiarity with statistical software such as Graphpad Prism.

• Proficiency in Python, R, bioinformatics/computational biology and statistical tools like Pymol, Chimera, BLAST, Alphafold, ggplot etc. Proficiency in deep learning models and/or knowledge of large language models (LLMs), prompt engineering, and experience in implementing these tools to biological questions is highly desirable.
• Experience with website and/or database design using various platforms such as HTML, JavaScript, ShinyR, PowerApps etc would be advantageous.

What We're Looking For

The ideal candidate will be:

• Self-motivated and a proactive self-starter with a strong drive for continuous learning and process/product improvement
• An excellent communicator-both written and oral-capable of clearly conveying findings to peers, collaborators, and leadership
• A collaborative team player who works effectively with diverse colleagues across functional and organizational boundaries
• Adaptable and flexible in navigating a fast-paced, evolving research environment with shifting priorities
• Detail-oriented with a commitment to scientific rigor, schedule adherence, and data integrity

Thermo Fisher Scientific is an equal opportunity employer, and we value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits and a company culture that stands for integrity, intensity, involvement, and innovation.