Scientist-Imaging Full-time

Molecular Imaging Scientist

The successful candidate will assist the lead molecular imaging scientist in executing projects in collaboration with various therapeutic focus areas, technology teams, and imaging scientists at Regeneron. Projects will include a mix of imaging novel therapeutic antibody candidates against molecular targets and imaging reporter genes expressed via transduction in a variety of disease conditions. These projects will be conducted using nuclear or optical imaging and ex vivo biodistribution studies aimed at profiling the in vivo pharmacokinetics and target engagement of lead antibody candidates or understanding biodistribution of genetic medicines in relevant small animal models. Current and emerging projects include work on targets, antibodies, and genetic medicines pertinent to oncology, cardiovascular disease, musculoskeletal disorders, and other therapeutic areas. Projects are constantly evolving and may change as new ideas and opportunities present themselves.

Responsibilities during a typical day might include the following:

• Working closely with the lead molecular imaging scientist to understand project needs and priorities, troubleshooting experiments, and providing updates on the progress of projects
• Independent execution of projects planned in consultation with the lead molecular imaging scientist and in collaboration with research associates from relevant therapeutic focus areas
• Handling small animals including routine dosing and anesthesia for in vivo imaging, and euthanasia followed by dissection for ex vivo biodistribution studies
• Setting up imaging and biodistribution experiments including organization of materials and reagents required for such studies
• Performing longitudinal PET/optical imaging experiments and ex vivo biodistribution studies
• Maintaining online and physical records of the data from ongoing and completed projects

This role may be for you if you:

• Are comfortable handling radioactivity and small animals for research
• A proven history of executing and accomplishing projects in a timely and independent manner within a laboratory setting is preferred
• Strong communication and interpersonal skills
• Prior experience with in vivo imaging and biodistribution studies using PET/CT, Cryo-Fluorescence Tomography, fluorescence, and bioluminescence will be highly preferred
• Prior experience with image analysis platforms such as VivoQuant, Amira, PMOD, Amide or similar is not absolutely required, but will be preferred
• A passion for biology and helping others
• Attention to detail, and due diligence in execution of projects
• Ability to shift focus between multiple projects while still meeting deadlines
• A proven ability to work independently and collaboratively as part of a larger project
• A dedication to share, collaborate, and lift up others
• A Bachelor's or Master's degree in science having at least 2-4 years of laboratory experience in preclinical in vivo imaging applications using small animal models.

Salary Range (annually): $93,900.00 – $153,300.00