Senior Associate Scientist Full-time

DMPK Sr. Associate Scientist (In Vitro ADME) – RayzeBio

RayzeBio, a Bristol Myers Squibb company, is a dynamic biotechnology company headquartered in San Diego, CA. The company is focused on improving survival of people with cancer by harnessing the power of targeted radioisotopes. RayzeBio is developing innovative drugs against targets of solid tumors. Led by a successful and experienced entrepreneurial team, RayzeBio aims to be the global leader in radiopharmaceuticals.

Position Overview

We are seeking a highly motivated Sr. Associate Scientist to join our growing Drug Metabolism and Pharmacokinetics (DMPK) team. This is a hands-on, laboratory-based role (100% on-site) focused on executing in vitro ADME assays to support drug discovery and development programs.

The ideal candidate is detail-oriented, organized, and collaborative, with strong communication and documentation skills.

Key Responsibilities

• Perform routine in vitro DMPK assays, including:
• Plasma protein binding (PPB)
• Plasma stability assays
• Execute experiments using established protocols (e.g., equilibrium dialysis-based methods) to assess drug binding, which is critical for understanding drug distribution, efficacy, and clearance
• Analyze and document experimental data with high accuracy and attention to detail
• Prepare clear, concise experimental records and summary reports
• Maintain organized laboratory notebooks and data systems
• Collaborate with cross-functional teams to support project timelines and deliverables
• Contribute to maintaining a high-quality, efficient lab environment
• Uses AI tools to enhance individual productivity and quality of work

Required Qualifications

• Bachelor's or Master's degree in a relevant scientific discipline (e.g., Pharmacology, Chemistry, Biology, or related field)
• Hands-on laboratory experience in a biotech, pharmaceutical, or academic setting
• Experience with LC-MS/MS analysis is required
• Strong organizational, documentation, and data integrity skills
• Effective written and verbal communication skills
• Ability to work both independently and as part of a collaborative team

Preferred Qualifications

• Experience with plasma protein binding assays, particularly using HTD (equilibrium dialysis systems)
• Familiarity with additional in vitro ADME assays
• Experience working in a fast-paced drug discovery environment

What We Offer

• A collaborative, science-driven environment with a strong team culture
• Opportunity to contribute to cutting-edge radiopharmaceutical therapies
• Exposure to innovative drug discovery programs in a rapidly growing biotech company

Why Join RayzeBio

At RayzeBio, we are committed to advancing transformative therapies for patients with cancer. You will be part of a highly collaborative and supportive DMPK team where your contributions directly impact the development of novel therapeutics.

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Compensation Overview:

San Diego – RayzeBio – CA: $95,505 – $115,730

The starting compensation range(s) for this role are listed above for a full-time employee (FTE) basis. Additional incentive cash and stock opportunities (based on eligibility) may be available. The starting pay rate takes into account characteristics of the job, such as required skills, where the job is performed, the employee's work schedule, job-related knowledge, and experience. Final, individual compensation will be decided based on demonstrated experience. Eligibility for specific benefits listed on our careers site may vary based on the job and location. For more on benefits, please visit https://careers.bms.com/life-at-bms/.

Benefit offerings are subject to the terms and conditions of the applicable plans in effect at the time and may require enrollment. Our benefits include:

• Health Coverage: Medical, pharmacy, dental, and vision care.
• Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
• Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.

Work-life benefits include:

Paid Time Off

• US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees)
• Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays

Based on eligibility*, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day.

All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.

*Eligibility Disclosure: The summer hours program is for United States (U.S.) office-based employees due to the unique nature of their work. Summer hours are generally not available for field sales and manufacturing operations and may also be limited for the capability centers. Employees in remote-by-design or lab-based roles may be eligible for summer hours, depending on the nature of their work, and should discuss eligibility with their manager. Employees covered under a collective bargaining agreement should consult that document to determine if they are eligible. Contractors, leased workers and other service providers are not eligible to participate in the program.

RayzeBio and Bristol Myers Squibb

RayzeBio was acquired by Bristol Myers Squibb (BMS) in 2024 and is a wholly-owned subsidiary of BMS; however, RayzeBio will continue to operate as a standalone organization.

Supporting People with Disabilities

BMS and RayzeBio are dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to adastaffingsupport@bms.com. Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS and RayzeBio will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If you believe that the job posting is missing information required by local law or incorrect in any way, please contact BMS at TAEnablement@bms.com . Please provide the Job Title and Requisition number so we can review. Communications related to your application should not be sent to this email and you will not receive a response.

R1603656 : Senior Associate Scientist