Senior Associate Scientist, Functional Genomics Full-time

Senior Associate Scientist, Functional Genomics

Location: Cambridge, MA

We are seeking a highly motivated and creative scientist to join the Functional Genomics cluster within the Target, Disease, and Systems Biology function in Sanofi Research. They will drive the application of functional genomics target ID and validation to advanced disease models in order to elucidate disease mechanisms and discover novel targets across immunology, ophthalmology, neurology, oncology, and rare disease. The successful candidate will collaborate closely with therapeutic area colleagues to advance functional genomics target discovery and validation and develop new screening workflows in advanced disease models including primary cells, iPSC-derived cells, and co-culture/organoid systems. This is a unique opportunity to work at the intersection of functional genomics, in vitro modelling, and disease biology to advance therapeutic target discovery.

Join the engine of Sanofi's mission — where deep immunoscience meets bold, AI-powered research. In R&D, you'll drive breakthroughs that could turn the impossible into possible for millions.

We're an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people's lives.

Main responsibilities:

• Perform experiments including pooled and arrayed CRISPR screens in human cellular disease models to validate targets and understand mechanism of action.
• Collaborate with senior researchers to develop and execute existing and novel cell-based assays to identify, validate, and translate high-value targets in diverse clinical indications.
• Develop cellular and molecular assays to study disease processes and validate targets in innovative disease models such as primary or iPSC-derived cells, co-culture systems, or organoids.
• Innovate in functional genomics technology by refining, scaling, or automating experimental methodologies to systematically explore gene function in disease contexts.
• Collaborate closely with therapeutic area experts to advance target discovery and in vitro disease modeling.
• Communicate your work in verbal, written and presentation formats.

About you:

• B.S. in biology or related field with a minimum of 5 years of industry experience.
• Hands-on experience in CRISPR genome editing or screening and disease modeling, especially in primary cells, is key.

Preferred:

• Experience in target or drug discovery, especially in immunology, ophthalmology, or neurology, would be highly valued.
• Experience with molecular and biochemical assays, such PCR/qRT-PCR/NGS, western blot, and flow cytometry.
• Excellent communication, organizational, and team skills with a track record of success working collaboratively across disciplines.

Why Choose Us:

• Bring the miracles of science to life alongside a supportive, future-focused team.
• Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs.
• Help improve the lives of millions of people globally by making drug development quicker and more effective.
• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

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