Our Company's Data, AI & Genome Sciences Department in Cambridge, MA is seeking a Senior Specialist (Senior Scientist), Data Science to join the Translational Neuroscience Analytics team and drive integrative analysis of spatial and single-nucleus multi-omics data from patients with neurodegenerative diseases.
The qualified individual will be a motivated data scientist or computational biologist with a track record of developing and applying cutting-edge AI/ML methodologies to extract actionable insights from single-nucleus and spatial multi-omics data. In this role, they will leverage spatially resolved transcriptomics data with single-cell resolution to understand target pathway biology in relation to pathological hallmarks of neurodegenerative diseases, especially Alzheimer's disease, and integrate this information with single-nucleus multi-omics data from large patient cohorts to enable causal modeling and prediction of target perturbation effects across cell populations of interest. Through these analyses, they will contribute to the evaluation of specific therapeutic hypotheses as well as the identification and placement of biomarkers along the causal cascade from therapeutic target to clinical outcome, ultimately shaping the translational strategies of our neurodegenerative therapeutic programs. They will work alongside with other data scientists and AI/ML scientists in the department to develop and apply innovative approaches to perform such analyses and further integration with clinical, genetic, and other omics data types. They will also be closely collaborating with cross-functional teams of data scientists, bench biologists, and clinical colleagues to drive our neuroscience biomarker and translational strategies.
Required Skills: Alzheimer's Disease, Computational Biology, Computer Science, Cross-Team Collaboration, Database Design, Data-Driven Decision Making, Data Engineering, Data Modeling, Data Science, Data Visualization, Machine Learning (ML), MultiModal AI, Neurodegenerative Diseases, Neuroscience, Omics, Programming Languages, Single Cell Analysis, Single-Cell Genomics, Spatial Data Analysis, Stakeholder Relationship Management, Teamwork, Transcriptomics
Preferred Skills: Foundation Model Fine Tuning, Foundation Models, Transformer Model
Tagged as: Life Sciences
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