Senior Scientist I, Analytical Development Full-time NEW

Senior Scientist I, Analytical Development

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

The Opportunity: We seek a Senior Scientist I, Analytical Development to join an experienced, fast-paced and collaborative team. This position will be primarily responsible for supporting characterization of AbbVie's mRNA-based targeted lipid nanoparticles (tLNPs) pipeline. This role will focus on executing testing methods for characterizing mRNA/tLNPs and supporting development of new tLNP characterization methods. Working collaboratively across the discovery research team, this position will support process/product characterization, expansion of the mRNA/tLNP pipeline, method development, and platform development.

Responsibilities & Duties:

• Independently perform icIEF, HPLC, CE, and plate-based assay testing of mRNA and tLNP products for characterizing content, purity/impurities, and integrity
• Support development of novel nanoparticle characterization techniques, including but not limited to icIEF, SEC, MALS, CZE, LC-MS, etc
• Re-optimize analytical methods to support new programs and platform improvements
• Improve routine assay efficiency through automation and assay/workflow improvements
• Author technical reports and documents as needed

Qualifications:

• Bachelors, Masters, or Ph.D. in Analytical Chemistry typically with a minimum of 10 (BS), 8 (MS), or 0 (Ph.D.) years related industry experience.
• Strong technical background in analytical chemistry, excellent analytical problem-solving skills. Capable of independently developing and troubleshooting analytical methods.
• Degree in Biochemistry, Chemistry, Bioengineering, Chemical Engineering or related field with experience testing and developing analytical characterization methods for biologics (e.g. antibodies, mRNA, etc) is required.
• Experience with nanoparticle and/or small molecule characterization is preferred
• Demonstrate creative 'out of the box' thinking to solve difficult problems
• Experience with icIEF, HPLC, Capillary Electrophoresis (CE), and plate-based assays required
• Proficiency authoring and reviewing technical reports
• Strong communication skills, both written and verbal, with a demonstrated capacity to thrive in collaborative, team-driven environments.

Compensation Range: $96,500 – 183,500 USD

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.