Senior Scientist I – Pharmacology Full-time

AbbVie In Vivo Imaging Scientist

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience – and products and services in our Allergan Aesthetics portfolio.

The Translational Sciences group, within Neuroscience Discovery Research, is actively engaged in an innovative research program dedicated to identifying and strengthening biomarkers and translational endpoints to support AbbVie's therapeutic programs. Working across the Neuroscience portfolio, with assets in neurodegeneration, movement disorders, psychiatry, and migraine, our comprehensive approach includes discovering and developing novel positron emission tomography (PET) radioligands, and their application (along with known radioligands) in drug discovery and development.

Within Translational Sciences the Molecular Imaging team leads pre-clinical and translational imaging activities working closely with other groups in AbbVie (e.g., medicinal chemists, biologists, pharmacologists, and clinicians), leading academics, and CROs. The responsibility of the In Vivo Imaging Scientist will be to lead and conduct preclinical PET imaging studies. The candidate will have access to state-of-the-art instrumentation and the opportunity to work with novel PET radioligands, animal models, and therapeutic drug approaches. This role operates in a collaborative culture and requires a high degree of matrix working both within the imaging function and across research departments.

Major Responsibilities:

• Function as the study coordinator of several preclinical imaging studies.
• Provide experimental support for preclinical PET imaging studies in rodents and large animals (e.g., formulation and administration of radiotracer/contrast agent/compound, image data acquisition, and blood sampling).
• Operate various imaging systems, including a Mediso LFER 150 PET/CT and a Mediso Nanoscan PET/CT.
• Handling & processing of plasma samples for, e.g., radiometabolite analysis via HPLC.
• Perform analysis of imaging data using specialized software.
• Develop and ensure high quality study protocols.
• Ensure maintenance of imaging equipment, in close collaboration with vendor support team.
• Communicate key results to team members and project stakeholders and contribute to study reports/publications.

Qualifications

• PhD in neuroscience, pharmacology, biomedical engineering, or a related field with typically 0-2 years of experience, or master's degree or equivalent education with typically up to 8 years of experience.
• Demonstrated skills in preclinical PET imaging.
• Ability to execute deadlines in multidisciplinary teams and deliver high quality data.
• Good publication record in international peer reviewed journals.
• Capacity to work effectively in multidisciplinary teams.
• Track record of successful collaborations/ building partnerships.
• Pharmaceutical industry experience preferred.
• Excellent analytical and problem-solving skills.
• Excellent oral and written communication skills.

Additional Information

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our long-term incentive programs.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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Pay Range:

$ 96500 – 183500 USD