Senior Scientist, Immunology & Inflammation Full-time

Senior Scientist

Regeneron is seeking a Senior Scientist to join a highly collaborative Immunology & Inflammation team. This individual will have the opportunity to support a broad pipeline in allergic and inflammatory diseases by validating targets, assessing the efficacy of therapeutic candidate molecules in vitro and in vivo, and interrogating mechanisms of pathology that inform therapeutic strategies. Candidate should have prior Immunology experience and prefer working in a team-driven environment, possess organizational skills and communicate openly and frequently with manager and team members.

A Typical Day May Include:

• Contributes to project advancement by developing new methods and technologies. Troubleshoots methodological and technical issues, interprets experimental data and literature, and communicates results to supervisor, department, or project team.
• Executes experiments based on projects/protocols provided and works towards independently developing project.
• Collaborates and communicates efficiently with team members to coordinate complex in vivo experiments, and with other departments to facilitate cross-functional efforts.
• Experience with proper handling and care of mice, general surgical techniques and the collection of blood and tissue samples.
• Develops and optimizes relevant disease mouse models and the subsequent analysis of associated disease-related pathologies by flow cytometry, histology and ELISA.
• Develops and executes cell-based assays to screen candidate antibodies for various research programs. Performs ELISAs and or MSDs to measure cytokine levels and determine antigen binding for various research programs.
• Contributes to lab and equipment maintenance and orders supplies/reagents to help create a safe, effective and efficient working environment.

This Role May Be For You If:

• You enjoy working in a fast-paced environment
• You are a fast learner and have desire to expand your skill set and learn new techniques
• You are detail oriented, well-organized and can multi-task
• You are a great teammate
• You have strong communication skills

To Be Considered, You Must Have The Following:

• Ph.D + 0-2+ years experience. The ideal candidate will be skilled in the design of complex studies to interrogate the in vivo efficacy of novel therapeutics and thus, will have experience with developing and optimizing mouse models of inflammatory diseases and analysis of associated disease-related pathologies by flow cytometry, histology and ELISA.
• Qualified applicants will preferably have minimum of 5-8 years of relevant research experience in immunology. Ph.D. in Biology, Immunology, or Cellular and Molecular Biology preferred but not required.
• Extensive experience with multi-parameter flow cytometry, panel design and data analysis is required.
• Basic computer literacy and experience collecting and analyzing biological data on the computer is a necessity. Preferred experience with the following data analysis programs: GraphPad PRISM, Softmax Pro, FlowJo analysis, HALO, DIVA software.
• Knowledge of allergic and inflammatory diseases, with emphasis in skin and/or lung biology is preferred.
• Preferred experience developing and optimizing primary cell assays used to characterize cytokine and immunoreceptor pathways and screen antibody candidates.
• Must have a record of high-quality publications in scientific literature.
• The candidate is expected to have effective verbal communication and written skills.