Senior Scientist, Manufacturing – Process Development Full-time NEW

Senior Scientist, Manufacturing – Process Development

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”—a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Key Responsibilities

• Provide technical leadership and subject matter expertise for downstream unit operations supporting commercial biologics manufacturing.

• Led tech transfer of commercial and pipeline assets to the Cruiserath facility and wider network, providing technical oversight and recommendations.

• Lead or support process troubleshooting, root cause analysis, investigations and the development of scientifically sound corrective and preventive actions.

• Design, execute and interpret laboratory or scale-down studies that support manufacturing investigations, process understanding and technology transfer.

• Author and review study protocols, technical reports, scientific assessments, regulatory submission content and responses to technical enquiries.

• Drive continuous improvement initiatives that enhance process robustness, efficiency, compliance and knowledge management.

• Collaborate across MS&T, Manufacturing, Quality, Process Development, Analytical, Regulatory and external partner organisations to align technical strategy and execution.

• Evaluate emerging downstream technologies and recommend fit-for-purpose improvements where these could strengthen manufacturing performance.

• Mentor and coach scientists and engineers, supporting effective technical decision-making and the development of downstream capability.

Technical Scope

The role may support technical studies and manufacturing activities across the following downstream operations:

• Protein chromatography
• Viral inactivation
• Viral filtration
• Ultrafiltration and diafiltration
• Membrane and depth filtration
• Primary recovery and centrifugation
• Process-scale and laboratory-scale downstream equipment, including chromatography and filtration systems

Required Qualifications and Experience

• Degree in chemical or biochemical engineering, biochemistry, biotechnology or a related scientific discipline.

• Relevant biopharmaceutical industry experience commensurate with the Senior Scientist level. As an initial benchmark: bachelor's degree with at least 7 years, master's degree with at least 5 years, or PhD with approximately 2 to 4 years of relevant experience.

• Strong scientific understanding of protein purification, protein stability and downstream process performance.

• Demonstrated experience with downstream processing operations and equipment, including chromatography and ultrafiltration/diafiltration systems.

• Experience supporting commercial manufacturing, process development, technology transfer, validation or manufacturing investigations in a regulated environment.

• Ability to independently analyse complex technical issues, integrate multiple data sources and develop clear, evidence-based recommendations.

• Strong technical writing, presentation and stakeholder communication skills.

• Working knowledge of GMP expectations and the potential manufacturing and regulatory impact of technical decisions.

Preferred Qualifications

• Experience with process characterisation, scale-down model qualification or continued process verification.

• Experience leading technical transfer activity and support commercial manufacture

• Experience authoring or contributing to CMC documentation and supporting regulatory inspections or technical responses.

• Demonstrated experience mentoring colleagues or providing technical leadership within cross-functional teams.

• Experience applying structured problem-solving, statistical analysis or design of experiments to bioprocess challenges.

Core Competencies

Scientific leadership

Applies deep technical knowledge and sound judgement to complex downstream challenges.

Execution

Plans and delivers high-quality technical work with appropriate urgency, rigour and documentation.

Collaboration

Builds productive relationships across functions, sites and external partners.

Communication

Conveys technical data, risk and recommendations clearly to scientific and non-scientific audiences.

Problem-solving

Uses structured, evidence-based approaches to identify root causes and sustainable solutions.

Coaching

Shares knowledge, provides constructive guidance and helps build team capability.

Compliance mindset

Understands GMP impact and maintains high standards of data integrity and documentation.

Continuous improvement

Identifies and implements practical opportunities to improve robustness and efficiency.

Working Environment and Role Expectations

• Work is performed through a combination of office and laboratory-based activities, subject to site requirements.

• The role requires effective prioritisation across planned studies, manufacturing support and time-sensitive technical issues.

• The successful candidate is expected to work independently while maintaining close alignment with cross-functional stakeholders and site procedures.

• Occasional support outside standard working hours or travel may be required depending on manufacturing and technology transfer needs.

Why you should apply

• You will help patients in their fight against serious diseases
• You will be part of a company that encourages excellence and innovation, respects diversity, develops leaders and values its employees.
• You'll get a competitive salary and a great benefits package including, but not only, an annual bonus, pension contribution, family health insurance, 27 days of annual leave, access to BMS Cruiserath on-site gym and life assurance

We hire for skills and capabilities, not just credentials – if this role excites you, but doesn't perfectly match your resume, we encourage you to apply anyway.