Sr. Associate Scientist, Analytical – DPDT Full-time NEW

Sr. Associate Scientist

We are seeking a highly motivated Sr. Associate Scientist to support the laboratory based analytical method development and qualification within the Drug Product Development and Technology (DPDT) group. The DPDT team supports all stages of R&D work through commercial. You will be responsible for developing and qualifying analytical methods for assessing drug product stability of various drug products from pre-clinical to commercialization development.

A Typical Day in the Role Might Look Like:

• Develop analytical methods for drug products, with primary focus on peptides, and supporting focus on antibody–drug conjugates, siRNA, monoclonal antibodies, and bispecific antibodies
• Develop and qualify analytical methods for critical quality attributes to support formulation development, DP process development, and stability testing for programs in preclinical and clinical stage.
• Prepare, author, and review critical analytical technical documents, including analytical method procedures (SOPs), method performance reports, method transfer documents and chip into pharmaceutical development reports for completeness and correctness.
• Maintains full working knowledge of analytical techniques and instruments and applies appropriately to projects and identify and assess novel analytical methods and technologies.
• Evaluate, interpret and present data at team meetings.
• Collaborate with other team members in DPDT and other functional groups at Regeneron in supporting the program development.
• Maintain accurate and complete laboratory record, participate in general lab instrument maintenance, and perform trouble shooting independently.

This Role Might Be For You if You:

• Take direction and guidance for data-driven decision making, priority setting and technical problem solving.
• Generate and organize data figures and data tables in a clear and insightful way
• Communicate critical data in timely manner to supervisor and team
• Possess strong ability to prioritize and manage multiple tasks effectively.
• Are highly organized, detail-oriented, self-motivated, effective team player.
• Have Excellent oral and written communication skills.

This role requires a BS degree in Chemistry, Chemical Engineering, Biochemistry, or related field with ≥4 years of research experience, or MS degree in the above-mentioned fields with ≥ 2-years of hands-on research experience.

Familiarity with the quantitative and qualitative techniques used in peptide and/or biologic drug products, including capillary and microchip electrophoresis, HPLC/UPLC, mass spectrometry a plus. Experience in biophysical characterization techniques such as DLS, HIAC, and ThT fluorescence assays is a plus.

The ability to work independently to design experiments, as well as interpret, document and communicate results is required.