Sr Scientist, Biologics Characterization Full-time

Senior Scientist

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Senior Scientist to join our Product Biochemistry team, driving late-stage development (Phase II through commercialization) of biologics. You'll develop and deploy analytical methods and purification strategies, enrich and characterize product variants, and help onboard new technologies that deepen product understanding and improve processes across the pipeline. You'll work in a fast-paced, team-based environment, partnering with cross-functional colleagues across Product Biochemistry and Regeneron to drive process improvements and technology initiatives.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY
• Work model/flexibility: Onsite

Discover your role:

• Develop analytical methods and purification protocols to support extended characterization of therapeutic proteins and gene therapy vectors
• Conduct biochemical/biophysical characterization to support development, regulatory submissions, and commercialization
• Apply DOE, advanced statistics, and risk assessments to evaluate and optimize methods and processes
• Design and execute experiments to enrich, purify, and characterize size/charge variants, complexes, and high-concentration formulations
• Author high-quality technical documents, including protocols, reports, memos, and contribute to regulatory sections and publications
• Integrate learnings from internal data and external literature to make science-based study design recommendations
• Lead or participate in technology initiatives and continuous improvement projects; may mentor junior analysts in a matrix-based environment
• Maintain instruments, troubleshoot instrumental and experimental issues, and improve lab and data workflows

This role might be for you if:

• You possess strong lab skills in protein separation, purification, and tangential flow filtration (TFF), along with mass spectrometry-based identification
• You thrive in a fast-paced, team environment and can also work independently across multiple projects
• You demonstrate initiative, calculated risk-taking, and a passion for innovation and continuous improvement
• You communicate clearly, manage projects effectively, and solve complex problems with data-driven rigor
• You're scientifically creative, hardworking, efficient, and flexible
• You enjoy mentoring others and contributing to a safe, efficient, and inclusive lab environment

This role requires:

• BS/MS/PhD in Biochemistry, Biophysics, or related field, plus 8-10+ years of experience (BS/MS) or 0-2+ years of experience (PhD)
• Technical proficiency in automated FPLC and/or HPLC (SEC, IEX, affinity), electrophoresis (capillary or microchip, SDS-PAGE, western blots), spectroscopy, and light scattering
• Fundamental understanding of protein structure/function, mass spectrometry, and immunology/immunogenicity
• Excellent oral and written communication skills, along with demonstrated teamwork
• Strong initiative to complete tasks, learn new technologies, and commit to continuous learning
• Ability to manage multiple priorities in a fast-moving R&D environment and communicate clearly with key stakeholders

Preferred / nice-to-haves:

• Experience working in the biopharmaceutical industry

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$109,900.00 – $179,300.00