Sr. Scientist, Stromal Immunology Full-time NEW

Senior Scientist in Stromal Immunology

Join our Immunology team in Cambridge, Massachusetts, and help shape the future of treatments for inflammatory and autoimmune diseases. In this role you will evaluate and apply novel experimental approaches, partnering across departments with discovery teams to implement cutting-edge laboratory technologies. You will drive the identification of innovative therapeutic targets and contribute directly to the development of new therapies and medicines that improve patient lives. This is an opportunity to work at the forefront of immunology research, translating scientific advances into meaningful clinical impact.

We are seeking an enthusiastic scientist with a strong track record of delivering timely, robust data packages. The ideal candidate will be able to work independently, able to design and execute their own experiments, and comfortable taking projects from conception through to clear, reproducible results. You should be proactive in problem-solving, able to communicate findings effectively to multidisciplinary teams, and committed to advancing research that leads to novel therapies and improved patient outcomes.

What you will do:

• Design and execute experiments, analyze and interpret complex dataset to identify and validate novel targets in immunology/ inflammation/autoimmunity
• Apply knowledge of key signal transduction pathways to design appropriate experiments
• Be a key contributor in lab and in meetings to progress multiple programs
• Conceptualize and enact innovative approaches (including novel technologies) to solve program objectives and issues
• Manage project-specific milestones and timelines
• Communicate science and strategy to stakeholders and management
• Collaborate effectively both internally & externally, within and across functional areas
• Demonstrates a “one-team” mindset by proactively engaging in and leadership of lab and department initiatives
• Actively participates in cultural initiatives & embraces DE&I principles, promotes psychological safety and supports a work environment that positively influences others and enables all to bring their true selves to work

What you will need to be successful in this role:

Required Experience:

• B.Sc in Biological Sciences, Immunology, Pathology, Biochemistry, Biotechnology, Biomedical Engineering, or related STEM field with 7+ years of professional research experience, M.Sc. with 4+ years of professional research experience or PhD and 0+ years of experience.
• Strong knowledge of immunology and cell biology. Experience with primary stromal cell cultures preferred
• Practical experience in performing and analyzing complex multicellular systems
• Ability to interpret and analyze data from key biological, biochemical and immunological assays systems and design appropriate follow up experiments
• Knowledgeable in immunofluorescence microscopy / high-content imaging and multi-color flow cytometry preferred
• Preferred: knowledge of inflammatory and/or auto-immunity related mechanisms of disease

Skills/Competencies

• Ability to adapt to changing priorities
• Passion for innovation and problem-solving
• Team player with effective written and oral communication skills
• Good organizational and time management skills

Required Skills:

3D Cell Culture, Autoimmune Diseases, Cell Cultures, Cytotoxicity, Fibrosis, Flow Cytometry, High Content Screening, Immunoassays, Immunology, Inflammatory Diseases, Molecular Biology, Multi-Color Flow Cytometry, Primary Cell Culture, Tissue Cell Culture

Preferred Skills:

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US and Puerto Rico Residents Only:

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The salary range for this role is $119,100.00 – $187,500.00

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days. More information about benefits is available at https://jobs.merck.com/us/en/compensation-and-benefits.

You can apply for this role through https://jobs.merck.com/us/en (or via the Workday Jobs Hub if you are a current employee). The application deadline for this position is stated on this posting.

San Francisco Residents Only: We will consider qualified applicants with arrest and conviction records for employment in compliance with the San Francisco Fair Chance Ordinance

Los Angeles Residents Only: We will consider for employment all qualified applicants, including those with criminal histories, in a manner consistent with the requirements of applicable state and local laws, including the City of Los Angeles' Fair Chance Initiative for Hiring Ordinance

Search Firm Representatives Please Read Carefully Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status: Regular

Relocation: Domestic

VISA Sponsorship: Yes

Travel Requirements: No Travel Required

Flexible Work Arrangements: Not Applicable

Shift: Not Indicated

Valid Driving License: No

Hazardous Material(s): OEB4, BSL2

Job Posting End Date: 05/15/2026

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