Postdoctoral Research Associate Full-time

The Faltas Lab at Weill Cornell Medicine in New York City https://faltaslab.weill.cornell.edu/ is seeking postdoctoral fellows and research associates with a background in cancer biology, computational biology, and bioinformatics to lead several projects including:

– The role of germline and somatic variants as immunogenomic determinants of treatment response and bladder cancer evolution.

-The role of the APOBEC3 family of cytidine deaminases in chromothripsis, genomic instability, and bladder cancer evolution.

These projects are funded by recent grants from the Starr Cancer Consortium and the P-1000 Consortium, and the Albert Institute for Bladder Cancer Research. Our well-funded and diverse laboratory is a vibrant and stimulating environment for scientific growth and fostering the independent careers of postdoctoral trainees.

Relevant publications:

Shohdy KS, Villamar DM, Cao Y, Trieu J, Price KS, Nagy R, Tagawa ST, Molina AM, Sternberg CN, Nanus DM, Mosquera JM, Elemento O, Sonpavde GP, Grivas P, Vogelzang NJ, Faltas BM. Serial ctDNA analysis predicts clinical progression in patients with advanced urothelial carcinoma. British Journal of Cancer. 2022 Feb;126(3):430-439. doi: 10.1038/s41416-021-01648-8. Epub 2022 Jan 19.

Vosoughi A, Zhang T, Shohdy K, Vlachostergios P, Wilkes D, Bhinder B, Tagawa S, Nanus D, Molina A, Beltran H, Sternberg C, Motanagh S, Robinson B, Xiang J, Fan X, Chung WK, Rubin M, Elemento O, Sboner A, Mosquera JM, Faltas BM. Common germline-somatic variant interactions in advanced urothelial cancer Nature Communications. 2020 Dec 3;11(1):6195.

doi: 10.1038/s41467-020-19971-8.

Robinson BD, Vlachostergios PJ, Bhinder B, Liu W, Li K, Moss TJ, Bareja R, Park K, Tavassoli P, Cyrta J, Tagawa ST, Nanus DM, Beltran H, Molina AM, Khani F, Miguel Mosquera J, Xylinas E, Shariat SF, Scherr DS, Rubin MA, Lerner SP, Matin SF, Elemento O, Faltas BM. Upper tract urothelial carcinoma has a luminal-papillary T-cell depleted contexture and activated FGFR3 signaling. Nature Communications. 2019 Jul 5;10(1):2977. doi: 10.1038/s41467-019-10873-y.

Vlachostergios PJ, Faltas BM. Treatment resistance in urothelial carcinoma: an evolutionary perspective. Nature Reviews Clinical Oncology. 2018 Aug;15(8):495-509. doi: 10.1038/s41571-018-0026-y.

Faltas BM, Prandi D, Tagawa ST, Molina AM, Nanus DM, Sternberg C, Rosenberg J, Mosquera JM, Robinson B, Elemento O, Sboner A, Beltran H, Demichelis F, Rubin MA. Clonal evolution of chemotherapy-resistant urothelial carcinoma. Nature Genetics. 2016 Dec;48(12):1490-1499. doi: 10.1038/ng.3692.

Requirements: 

Ph.D. with a background in cancer biology, bioinformatics, computational biology, or related fields. The Ph.D. awarded/expected date should be between 2020-2023.
For cancer biology positions, experience in molecular biology and biochemistry techniques.
For bioinformatics postdoctoral and research analyst positions, experience in high-level programming languages (e.g., R, Python, Perl), experience in computational biology applications, and next-generation sequencing are required. The position offers opportunities for close collaboration with the world-class bioinformatics team at the Englander Institute for Precision Medicine.
Evidence of productivity from publications originating from Ph.D.
Excellent verbal and written communication skills.
Excellent organizational skills, self-motivation, and creativity.
Motivated to pursue postdoctoral training required for a future independent academic career.
Candidates who meet the above criteria are encouraged to apply. Please email CV, statement of research interests, copies of previous publications, and the names and contact information for three references to Dr. Bishoy Faltas bmf9003@med.cornell.edu

Tagged as: Life Sciences