Postdoc in Microglial Biology and Single-Cell Multi-Omics Full-time NEW

Postdoc in Microglial Biology and Single-Cell Multi-Omics

Apply DANDRITE at the Department of Biomedicine at the Faculty of Health at Aarhus University invites applications for a position as a Postdoc in microglial biology and single-cell multi-omics as of 1 August 2026 or as soon as possible thereafter. The position is a fixed-term full-time position for 2 years.

About the research project: The position is funded by the Independent Research Fund Denmark (DFF-Research Project 1, FNU) and is part of a research programme investigating how microglial states emerge during development and how the same regulatory logic shapes microglial behaviour and neuronal vulnerability. The successful candidate will lead the computational and integrative arm of a project on the epigenetic and transcriptomic drivers of microglial ontogeny in early brain development. This includes constructing high-resolution single-cell transcriptomic and chromatin atlases of microglia, inferring regulatory networks underlying lineage diversification, and integrating these maps with spatial and perturbation datasets generated in the laboratory. The role is anchored in the developmental programme but extends across the wider laboratory, which has generated single-cell, single-nucleus, and spatial multi-omics resources spanning disease models, multiple brain regions, developmental and aging stages, and key genetic perturbations. The successful candidate will have access to these datasets and is expected to contribute computational leadership across linked projects within the lab.

Your job responsibilities: As a Postdoc, your position is primarily research-based but may also involve limited teaching assignments. You will contribute to the development of the department through research of high international quality. Your main tasks will consist of:

• Independent research of high international quality, including publication
• Computational analysis and integration of large-scale single-cell, single-nucleus, and spatial omics datasets
• Development of analytical or quantitative approaches to study cell-state transitions, lineage relationships, and regulatory programmes
• Close collaboration with experimental researchers within the laboratory and with external partners
• Contribution to manuscript preparation, grant applications, and dissemination of results

You will report to Associate Professor Dong Won Thomas Kim.

Your competences: You have academic qualifications at the PhD level in computational biology, bioinformatics, systems biology, neuroscience, or a related field. In addition, we expect:

• Strong experience with single-cell and/or spatial omics data analysis
• Proficiency in Python and/or R and modern data analysis workflows
• A track record of independent first-author research
• Ability to work independently and collaboratively in an interdisciplinary environment
• Strong written and spoken English

Preferred qualifications include:

• Experience with multi-modal data integration (e.g., scRNA-seq with scATAC-seq or spatial data)
• Background in lineage tracing, developmental biology, or cell-state modelling
• Familiarity with regulatory network inference or chromatin analysis
• Interest in neurobiology, immunology, or neurodegenerative disease
• Familiarity with mouse models; FELASA certification is welcome but not required

As a person, you have good interpersonal skills, are inclusive and team-oriented, and are able to contribute to a good work environment. Shortlisting will be used.

Questions about the position: If you have any questions about the position, please contact Associate Professor Dong Won Thomas Kim (tkim@dandrite.au.dk). Your place of work will be the Department of Biomedicine, Høegh-Guldbergs Gade 10, DK-8000 Aarhus C, Denmark. We expect to conduct interviews in June 2026.