Postdoctoral Researcher in radiotherapy induced skin side-effects research Full-time

Postdoctoral Researcher in Radiotherapy Induced Skin Side-Effects Research

Do you want to contribute to top quality medical research?

The Department of Medicine, Solna, is one of the largest departments at Karolinska Institutet. The core activities of the department are research, doctoral education and undergraduate education for medical and biomedical students. The research has three main profiles: allergy, cardiovascular medicine and inflammatory diseases.

Your Mission

We are seeking a highly motivated postdoctoral fellow to join our research group investigating the cellular and molecular mechanisms underlying radiotherapy-induced skin side effects and impaired wound healing. Radiotherapy is a cornerstone of cancer treatment, yet many cancer survivors experience long-term skin damage, fibrosis, and delayed tissue repair that significantly affect their quality of life.

The successful candidate will contribute to ongoing projects aimed at understanding how radiation exposure induces persistent changes in skin cells and their microenvironment. The research combines advanced molecular biology, genomics, single-cell and spatial omics technologies, as well as human clinical samples and experimental models to identify novel therapeutic targets for improving tissue regeneration after radiotherapy.

Your Profile

Required skills of the successful candidate are:

• A PhD in the area of molecular biology, cell biology or biochemistry
• Extensive experience with tissue culture, molecular and biochemical techniques
• Extensive experience in research within skin biology, wound healing, radiation biology, or regenerative medicine
• Documented ability to deliver high-quality scientific outputs with a strong publication record
• Good interpersonal skills and the ability to work both independently but also as a part of a large research team
• Very good knowledge of spoken and written English
• Good communication skills

We will look favorably upon if the candidate has experiences in one or more of the following areas:

• Animal models for studies of tissue regeneration, radiation-induced injury, or wound healing
• Histological techniques, including immunohistochemistry, immunofluorescence, and in situ hybridization
• Flow cytometry and cell sorting
• Single-cell and spatial omics technologies
• Analysis of transcriptomic, epigenomic, or other large-scale omics data
• Working with human clinical samples
• Method development and implementation of novel experimental techniques

To be eligible for employment as a postdoctoral researcher, a PhD or a foreign degree deemed to be equivalent to a Swedish PhD is required. This eligibility requirement must be fulfilled at the latest at the time of the employment decision. Completion of your doctoral degree within the last three years is considered an advantage. If there are special reasons, your degree may have been completed earlier.

What Do We Offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. At Karolinska Institutet, we conduct successful medical research and hold the largest range of medical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Karolinska Institutet is also a state university, which entitles you to several benefits through our collective agreement.

Location

The position is located within the Department of Medicine, Solna. The department consists of ten divisions, and each division consists of several research groups. The position is located within the research group of Associate Professor Ning Xu Landén and is physically located at the Centre of Molecular Medicine (CMM). The research is performed in an interdisciplinary setting with strong collaboration with clinical departments and other national and international research groups.

The research group conducts research on skin regeneration, wound healing, and the long-term effects of radiation therapy on the skin. By combining unique patient materials with advanced methods in molecular biology, single-cell and spatial omics, the group aims to understand the cellular and molecular mechanisms underlying impaired tissue repair and to identify new treatment strategies for patients with radiation-induced tissue damage.

Application

An employment application must contain the following documents in English or Swedish:

• PhD certificate
• A complete resumé, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

KI applies individual and differentiated salary setting in accordance with our collective agreements RALS and RALS-T

The application is to be submitted through the Varbi recruitment system.

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