Postdoctoral studies in Heart Regeneration (scholarship) Full-time NEW

Postdoctoral Studies In Heart Regeneration (Scholarship)

Do you want to contribute to top quality medical research?

Salamanders possess extraordinary regenerative abilities and remarkable resistance to tumor formation. We are seeking an ambitious postdoctoral researcher to investigate the role of cell-cell junctions, signaling and mechanical cues in terminating regenerative programs in the salamander heart. This project is supported by European Research Council and aims to uncover fundamental principles of tissue regeneration and its regulation, with potential implications for regenerative medicine and cancer biology.

Division

The research group led by Principal Researcher Dr. Elif Eroglu focuses on how mechanical cues guide cardiac regeneration using the Iberian-ribbed newt as a model. Our work is primarily directed towards epicardium, the outer layer covering the heart, and its interaction with the cardiac muscle. We use advanced methods to study regenerative programs running in parallel in the newt heart, their coordination and their timely termination.

Duties

We are seeking a highly motivated postdoctoral researcher to join our team for an exciting project focused on understanding how regeneration is terminated in a timely manner. The overarching aim is to explore how cell proliferation and differentiation are controlled and coordinated in relation to the changing physical properties of the regenerating heart. The project will utilize our dedicated state-of-the-art two-photon microscope and will involve small animal surgeries, basic molecular biology assays, force measurements, epigenetic and transcriptomic analysis. This analysis will be integrated with complimentary approaches such as function and -omics data.

The chosen candidate is embedded in a vibrant and interdisciplinary research environment, offering excellent opportunities for scientific development, collaboration, and career advancement.

Entry Requirements

The ideal candidate will have a background in cell and molecular biology with experience in mechanotransduction and regenerative biology and a deep passion for microscopy. Previous experience working with a regenerating organism and/or non-traditional model will be meriting. Completion of your doctoral degree within the last two years is considered an advantage. Strong data analysis skills are essential. Experience working in Matlab, R, Python, or similar programming environments, and a demonstrated ability to integrate and interpret multi-modal datasets, will be considered a major asset.

What Do We Offer?

A creative and inspiring environment with wide-ranging expertise and interests. Karolinska Institutet is one of the world's leading medical universities. Here, we conduct innovative medical research and provide the largest range of biomedical education in Sweden. At KI, you get to meet researchers working with a wide range of specialisms and methods, giving you ample opportunity to exchange knowledge and experience with the various scientific fields within medicine and health. It is the crossover collaborations, which have pushed KI to where it is today, at the forefront of global research. Several of the people you meet in healthcare are educated at KI. A close relationship with the health care providers is important for creating groundbreaking top quality education and research. Students and employees have free access to our modern gym facilities with trained staff on site.

Application Process

An application must contain the following documents in English or Swedish:

• A complete curriculum vitae, including date of the thesis defence, title of the thesis, previous academic positions, academic title, current position, academic distinctions, and committee work
• A complete list of publications
• A summary of current work (no more than one page)

The application is to be submitted on the Varbi recruitment system.