Process Dev Engineering Scientist Full-time

Scientist, Process Development

Vertex is seeking a talented and motivated Scientist to join our Process Development team. The Process Development Engineering Scientist will lead projects focused on process development, optimization, and characterization of cell therapy products for current and future programs. This role involves hands-on work with large-scale bioreactors (50L and above) and will focus on developing scalable media and bioreactor processes to advance our Type 1 Diabetes program.

Key Responsibilities

• Design and execute experiments to develop robust manufacturing processes for cell therapy products and support programs in clinical development.
• Develop robust, scalable media and bioreactor processes for cell therapy manufacturing.
• Evaluate novel and emerging technologies to advance project strategies.
• Lead projects within the team and provide training and support to scientists and engineers in large-scale bioprocessing and media scale-up.
• Apply deep knowledge of cell culture, bioreactor operations, and scale-up principles to process development activities.
• Use scientific and engineering fundamentals to support process design, development, and process understanding.
• Apply statistical tools and design of experiments (DOE) to guide process optimization.
• Develop process development and optimization strategies for 50L scale and beyond.
• Drive development activities in a cross-functional team environment.
• Author and review batch records, technical reports, and supporting documentation.
• Troubleshoot and resolve process challenges through the application of technical expertise and scientific judgment.
• Troubleshoot process and equipment-related issues and apply a strong understanding of large-scale bioprocessing equipment to support operations.

Knowledge and Skills

• Experience in large-scale bioprocessing, including operation of 50L and above bioreactors.
• Strong understanding of large-scale bioprocessing equipment and demonstrated ability to troubleshoot equipment and process issues.
• Strong background in design of experiments (DOE) and statistical analysis.
• Strong understanding of cell culture processes and bioreactor scale-up.
• Excellent verbal and written communication skills, with the ability to communicate complex technical and scientific information clearly.
• Ability to manage multiple priorities, meet timelines, and adapt in a fast-paced environment.

Qualifications

• Bachelor's degree in Chemical Engineering, Bioengineering, Biochemistry, Biology, or a related field with 6–8 years of relevant experience, or Master's degree with 4–6 years of relevant experience, or PhD with 0–3 years of relevant experience.

Pay Range: $104,000 – $156,000

Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for this job at the time of posting. This role is eligible for an annual bonus and annual equity awards. Some roles may also be eligible for overtime pay, in accordance with federal and state requirements. Actual base salary pay will be based on a number of factors, including skills, competencies, experience, and other job-related factors permitted by law.

At Vertex, our Total Rewards offerings also include inclusive market-leading benefits to meet our employees wherever they are in their career, financial, family and wellbeing journey while providing flexibility and resources to support their growth and aspirations. From medical, dental and vision benefits to generous paid time off (including a week-long company shutdown in the Summer and the Winter), educational assistance programs including student loan repayment, a generous commuting subsidy, matching charitable donations, 401(k) and so much more.

Flex Designation: On-Site Designated

Flex Eligibility Status: In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information: Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com