Research Fellow Full-time

Research Fellow

We are seeking a highly motivated Research Fellow to join the PARK-SEED study at the UCL Queen Square Institute of Neurology. This ambitious project aims to develop and apply alpha-synuclein and tau seed amplification assays (SAAs) to improve the diagnosis and prognosis of Parkinson's disease (PD) and progressive supranuclear palsy (PSP), support clinical trials and identify novel disease-modifying targets.

You will lead the development and implementation of tau SAAs, including tau substrate purification, and apply these assays to clinical and post-mortem patient samples. You will analyse data, contribute to publications, supervise early career researchers and have opportunities to develop your own research projects.

Working with clinicians and researchers across UCL, the UK Dementia Research Institute and international collaborations, you will develop expertise in SAA techniques, genetic analysis and clinical research, with opportunities to publish and present your findings at national and international conferences.

The post would be particularly suited to someone with a background in biochemistry, protein chemistry, molecular biology or a related discipline, and a PhD in a relevant subject area. Experience in the development and use of tau seed amplification assays (tau SAA), including tau substrate expression and purification, would be desirable.

You will be comfortable working on your own initiative and taking a self-directed approach, with excellent organisational skills and the ability to work collaboratively within a multidisciplinary research team while maintaining independent thinking. A proactive approach to problem-solving and troubleshooting will be essential as this ambitious project progresses.