Scientist I, Bioanalytical R&D – Bioassay Full-time

Associate Scientist II / Scientist I

We are seeking a highly motivated Associate Scientist II / Scientist I to join our Bioanalytical team. This is a hands-on laboratory role focused on developing, executing, and optimizing bioassays to assess the potency of pharmaceutical products. The successful candidate will support analytical testing and method development using a range of cell-based assay techniques. The ideal candidate is eager to learn, highly detail-oriented, and able to generate high-quality data in face-paced environments.

The Analytical Development group within the Targeted LNP (tLNP) CMC Team at AbbVie is dedicated to advancing analytical capabilities for mRNA-lipid nanoparticle therapeutics. Our team supports drug substance (DS) and drug product (DP) manufacturing and drug product formulation by implementing state-of-the-art analytical methodologies to ensure the quality, safety, and integrity of tLNP genetic medicines. Collaboration is central to our work; we partner directly with CMC, drug product formulation groups, and external collaborators, and are currently building a world-class team of scientists who will be instrumental in assembling the analytical toolbox needed to deliver high-quality, innovative tLNP medicines to patients.

Key Responsibilities:

• Execute routine and non-routine cell-based potency assays using various mammalian cell lines to characterize and evaluate potency of pharmaceutical products to support timely delivery of data packages.
• Organize and maintain cell inventories, laboratory instruments, reagents, consumables, and overall lab organization to ensure smooth workflow and compliance.
• Assist in the development, optimization, qualification, and troubleshooting of bioanalytical methods to meet project and departmental needs.
• Analyze, interpret, and clearly document experimental data, observations, and conclusions in laboratory notebooks and electronic systems.
• Prepare data summaries and present findings to team members and cross-functional partners.
• Troubleshoot assay performance issues and help identify practical solutions to improve robustness, reproducibility, and efficiency.
• Collaborate effectively with scientists and cross-functional colleagues to support timelines, project goals, and scientific decision-making.
• Contribute technical reports, study summaries, SOPs, and other scientific documentation as needed.
• Follow applicable laboratory practices, safety procedures, and company standards for data integrity and documentation.

Qualifications:

Required Education:

• Associate Scientist II: Bachelor's Degree, or equivalent education, with typically 3 or more years' experience or Master's Degree or equivalent education (no additional experience).
• Scientist I: Bachelor's Degree or equivalent education with typically 5 years of experience, or Master's Degree or equivalent education with typically two years of experience.

Required Skills and Experience:

• Extensive hands-on experience with cell-based assays and flow cytometry analysis.
• Experience in immunology research, especially cell therapy.
• Experience generating, analyzing, and interpreting experimental data with strong attention to detail.
• Ability to troubleshoot assays and optimize experimental conditions.
• Strong organizational skills with the ability to manage multiple experiments and priorities simultaneously.
• Effective written and verbal communication skills.
• Demonstrated ability to work independently and collaboratively in a team environment.
• Proficiency in maintaining accurate and complete scientific documentation using an electronic lab notebook system.

Preferred:

• Experience executing cell-based assays in GMP environments.
• Experience with method transfer to GMP environments.

Pay Range: $75000 – 142500 USD

Role is exclusively performed at a site or office and onsite presence is required. Employees who are site/office-based and can occasionally perform their role virtually work both in the office and remotely*, following the policies and regulations in place at their location. US Employees must be in the office on Tuesday, Wednesday, and Thursday with flexibility to work remotely on Mondays and Fridays. Three days in the office is the minimum; some individuals or teams may require more in-office days due to meetings, business/project needs or their role.