Senior Associate Scientist Full-time

Laboratory-Based Position in Analytical Development Group

This laboratory-based position is in the Analytical Development group within Vaccines. The primary functions of this role are to develop analytical assays in support of the extensive vaccine portfolio and to support the Critical Reagents tasks. The individual will collaborate closely with scientists across the Early BioProcess Development (EBPD) to design and implement cell-based potency assays for multiple vaccine programs. The individual will participate in regular vaccine development meetings and represent the group on multidisciplinary teams.

How You Will Achieve It

• Provide laboratory-based support for assay development, including ELISA and cell-based assays to support potency assay development.
• Perform in-vitro expression analysis of mRNA Drug Substance (DS) and Drug Products (DP) for multiple RNA vaccine programs.
• Support sample testing for process development, formulation development, critical reagents characterization and on-going stability studies.
• Analyze data using appropriate statistical software, such as GraphPad Prism and SoftMax
• Support the Critical Reagents qualification testing, delivery, and documentation
• Document experiments, data, and conclusions in an electronic lab notebook (ELN) contemporaneously.
• Contribute to authoring technical documents, including development reports, analytical lab methods, and method qualification reports.
• Review scientific and technical literature to stay current in the field.
• Present data in meetings within the department

Qualifications:

Must-Have

• BS degree in biological science, microbiology, immunology, or related fields with 2+ years relevant laboratory experience; OR a master's degree with more than 0+ years of experience.
• Background and experience in mammalian cell culture, DNA and RNA transfection, and reporter cell assays.
• Experience with ELISA assay.
• Experience with in vitro expression and flow cytometry.
• Knowledge of innate and acquired immunity, with the ability to apply this knowledge to test novel adjuvants.
• Proficiency in analytical software, including GraphPad Prism and SoftMax.
• Proficiency in computer skills including Microsoft Word, PowerPoint, and Excel.
• Strong organization skills
• Strong verbal and written communication skills.

Nice-to-Have:

• Experience with authoring development reports and lab methods
• Experience in documenting experiments using Signals electronic lab notebook

Physical/Mental Requirements

• Ability to work 40 hours/week in a laboratory setting
• Ability to perform data analysis

Work Location Assignment: On Premise

The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.

U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.