Senior Associate Scientist – Bioanalytical & Biomarker Technologies Full-time

Senior Associate Scientist

We are seeking a dynamic senior associate scientist to join bioanalytical & biomarker technologies group. The candidate will design and execute analytical and bioanalytical method to support biotherapeutics discovery and preclinical development. The individual should be experienced in executing HPLC and/or LC-MS based methods from sample preparation, instrument operation to data analysis. The successful candidate will be expected to work cross-functionally in a collaborative, fast-paced, multidisciplinary team environment and have the opportunity to explore new technologies while growing technical depth.

A typical day in this role looks like:

• Design, execute, and troubleshoot LC-MS and HPLC methods for analytical characterization of bioconjugates and bioanalytical quantification of therapeutics.
• Support a range of modalities—including monoclonal antibodies (mAbs), antibody–drug conjugates (ADCs), siRNA/oligonucleotides, and endogenous biomarkers—across diverse biological matrices.
• Perform end-to-end sample preparation (e.g., LLE, SPE, affinity capture, enzymatic digestion, homogenization) and operate LC-MS/MS workflows from instrument setup to data analysis.
• Analyze and interpret results; summarize findings, propose next steps, and present data at internal meetings.
• Document experiments, methods, and results in electronic lab notebooks (ELNs) with clarity and rigor; contribute to SOPs and method documentation.
• Maintain instruments and general lab readiness; troubleshoot systems and ensure data integrity and instrument uptime.
• Evaluate and implement new platforms, workflows, and automation to improve throughput, sensitivity, and robustness.
• Prioritize effectively across multiple projects and timelines, collaborating closely with colleagues in discovery biology, DMPK/PK-PD, and process/analytical teams.

This role may be for you, if you have experience:

• BS or MS degree in Chemistry, Biochemistry, Pharmaceutical Science or a related discipline with 3+ years hand-on experience.
• Experience in liquid chromatography and/or mass spectrometry is preferred, with the ability to execute, qualify and optimize analytical methods.
• Hands on experience in sample preparation techniques (LLE, SPE, affinity capture, enzymatic digestion, homogenization, etc.); experience with automation platforms is a plus.
• Detail-oriented, good interpersonal and effective technical communication skills (written and verbal).
• Ability to manage multiple projects in a fast-paced environment.
• Collaborative team player with a growth mindset to quickly adapt to evolving priorities and continuously learn to embrace new challenges.
• Previous exposure in bioanalysis of LC-MS based small molecule, oligonucleotides, biomarkers and biotherapeutics assay development is beneficial.