Principal Scientist, Precision Medicine Strategy Lead (Clinical Biomarkers) Full-time

Precision Medicine Strategy Lead (Principal Scientist)

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Precision Medicine Strategy Lead to join our Translational Medicine organization, supporting clinical biomarker strategy for multiple clinical-stage assets across our Immunology & Inflammation, Ophthalmology, and Infectious Diseases portfolios. In this role, you will shape biomarker strategies that enable endpoint selection, indication choice, and demonstration of target engagement and mechanism of action, while collaborating with research teams, clinical development, laboratory operations, companion diagnostics, and external academic and alliance partners.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

Location: Tarrytown, NY

Work model/flexibility: 4 days per week

Discover your role:

• Define and champion the strategic vision and scientific rationale for clinical biomarker plans across I&I, Ophthalmology, and/or Infectious Disease programs
• Represent Precision Medicine on clinical development teams, driving biomarker strategy from concept through execution and interpretation
• Partner with clinical and laboratory operations to implement biomarker and exploratory sample collection and analyses
• Ensure clinical biomarker assays are fit-for-purpose, whether developed internally or through external collaborators and CROs
• Present translational project plans, biomarker data, and results to internal and external stakeholders, including senior leadership
• Contribute high-quality Precision Medicine content to clinical protocols, study reports, data reviews, biomarker reports, and manuscripts/publications
• Translate complex immunology and disease biology into clear, testable biomarker hypotheses and decision criteria
• Navigate ambiguity and prioritize across multiple programs in a collaborative, matrixed environment

This role requires:

• Ph.D. with post-doctoral experience in Immunology or a closely related field highly desirable; 5+ years of relevant experience in pharmaceutical/biotech research and/or translational clinical development
• Exceptional communication skills and strong emotional intelligence, with enthusiasm for presenting to senior leaders
• Collaborative and innovative mindset, energized by working in a matrixed, cross-functional environment
• Understanding of biomarker strategy in clinical development, including assay development, validation, and implementation
• Preferred: track record of high-impact contributions to drug development programs
• Preferred: experience authoring industry documents (protocols, CSRs, biomarker reports)
• Alternative levels will be considered commensurate with experience.