Research Fellow Full-time

Research Fellow

The purpose of this Postdoctoral Research Fellow position is to structurally characterize Protein Quality Control Pathways including autophagy and proteasome degradation, crucial for clearing misfolded proteins implicated in neurodegenerative diseases.

The role will leverage cutting-edge structural and cellular methods, specifically cryo-Electron Tomography (cryo-ET), to resolve the architecture, both in vitro at atomic resolution and in situ within the native cellular environment.

• To undertake experimental and computational work, under the supervision of Dr. Zhao. • Ph.D. in Biochemistry, Structural Biology, or a related field (required). • Experienced in molecular cloning, protein expression, and purification for structural studies (required). • Prior experience with cryo-EM, cryo-ET data acquisition and processing, and cryo-FIB/SEM sample preparation (desired). • Prior experience with structure modelling or structural mass spectrometry (desired).

• To maintain accurate records of data analysis protocols from raw data to completed analysis results. • To attend research team meetings. • To prepare reports and presentations of laboratory work for seminars, manuscripts for publication, public engagement initiatives and funding bodies. • To contribute to the induction and direction of other research staff and students as requested. It is expected that the post holder will support other members of the Division and collaborators in their research roles in addition to developing their own project. • To contribute to the overall activities of the research team and department as required, including teaching and supervision of undergraduate or post-graduate students. • To actively follow UCL policies on Health and Safety, Race Equality, Equal Opportunities, Research Governance and Research Ethics.

The UCL Ways of Working supports colleagues to be successful and happy at UCL through sharing expectations around how we work.

As well as the exciting opportunities this role presents, we also offer some great benefits some of which are below:

• 41 Days holiday (27 days annual leave 8 bank holiday and 6 closure days)
• Additional 5 days' annual leave purchase scheme
• Defined benefit career average revalued earnings pension scheme (CARE)
• Cycle to work scheme and season ticket loan
• Immigration loan
• Relocation scheme for certain posts
• On-Site nursery
• On-site gym
• Enhanced maternity, paternity and adoption pay
• Employee assistance programme: Staff Support Service
• Discounted medical insurance

As London's Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world's talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.

These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.

Our division holds an Athena SWAN Bronze award, in recognition of our commitment to advancing gender equality.